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Sysmex West & Central Africa Academy Library Documents

Scientific documents library

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  • Xtra Article
  • Haematology
The clinical relevance of measuring NRBC in the XN-CBC

The term ‘NRBC’ – ‘nucleated red blood cells’ – refers to precursor cells of the red blood cell lineage which still contain a nucleus. In healthy adults and older children, NRBC can only be found in blood-building bone marrow where they mature. Their appearance in peripheral blood points to extramedullary erythropoiesis or disruption of the blood - bone marrow barrier. Both possible scenarios can only be found in the course of a severe disease.

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  • Xtra Article
  • Haematology
The Immature Granulocyte Count - The first to know about inflammation

The capability to count blood cells beyond the classical 5-part differential with high reliability is a challenge for modern haematology analysers. Sysmex offers the immature granulocyte count (IG) optionally on the XE-series and XT-series analysers. It is a standard diagnostic parameter on the XT-4000i, the XE-5000 and on the new XN-series as well.

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  • Diagnostic Perspectives
  • Haematology
The immature platelet fraction (IPF) in neonates

Thrombocytopenia occurs in 30% of all neonates admitted to intensive care. Young, immature platelets containing RNA, measured as “immature platelet fraction” (IPF) on Sysmex analyzers, can help to assess platelet production. Thus, they allow conclusions on both the etiology and the likely course of thrombocytopenia in neonates.

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  • SEED
  • Haematology
The importance of thrombocytopenia and its causes

Thrombocytopenia is a disorder in which there is an abnormally low amount of platelets. It can be life threatening and its detection and precise count is extremely important. The immature platelet fraction (IPF parameter) measures young, reticulated platelets in peripheral Blood, revealing if the bone marrow is producing or not.

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  • SEED
  • Haematology
The red blood cell indices

Sysmex Educational Enhancement and Development October 2012

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  • SEED
  • Coagulation
The role of the D-dimer test in clinical diagnostics

Sysmex Educational Enhancement and Development July 2012

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  • Diagnostic Perspectives
  • Haematology
Usefulness of NEUT-X determination in routine diagnostic procedures: application to myelodysplastic syndromes

Myelodysplastic syndromes (MDS) often go unnoticed when only a complete blood count is performed on the patient. Sysmex X-Class analysers can measure the granularity of leukocytes which is often reduced in MDS. NEUT-X, the measure of neutrophil granularity, is an excellent tool to filter samples suspected of MDS in anaemic patients.

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  • White Paper
  • Haematology
White blood cell functionality

By combining the WDF and WPC channels both the sensitivity and specificity for detecting reactive and malignant cells is optimised. The measurement technology of XN-Series analysers detects the white blood cell functionality and the novel ‘Extended Inflammation Parameters’ let you quantify activated lymphocytes and neutrophils, and the results can be applied once a malignancy has been excluded.

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  • White Paper
  • Flow Cytometry
White Paper Cytometry

Flow cytometry for the analysis of microorganisms (yeasts, bacteria ...)

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